Studies of Healthcare interventions
Primary studies
- Effect of needle size on incidence of local reactions and immunogenicity following routine immunisation of UK infants
- Pack size legislation to reduce suicide from paracetamol and salicylates
- A randomised controlled trial of tumour chemosensitivity assay directed chemotherapy versus physician's choice in patients with recurrent platinum-resistant ovarian cancer
- An international collaborative trial for relapsed and refractory acute lymphoblastic leukaemia - UKALLR3
- Randomised trial of an intervention for reducing delay in older patients with breast cancer
- Randomised trial to assess the impact of a leaflet on the decision to go for prostate cancer screening being fully informed consent
- QUASAR 2: Multicentre international study of 5-fluorouracil and folinic acid, vs capecitabine plus irinotecan as adjuvant treatment of colorectal cancer
- QUASAR 2 Mobile: Utilising handheld computers to improve symptom outcomes for patients receiving chemotherapy: the impact of an Electronic Symptom Management System on chemotherapy-related toxicity
- CREDO Phase 1: Can computer aided decision support help doctors choose the correct management path for patients undergoing triple assessment for possible breast cancer ?
- VICTOR PS: VIOXX in colorectal cancer therapy: definition of optimal regime polyp sub-study
- Smoking cessation trials in primary care
- Spine Stabilisation Trial: Management of chronic low back pain
- International Subarachnoid Aneurysm Trial (ISAT)
- A randomised controlled trial of a micronutrient rich, high fibre, low-energy density formula for gastrostomy feeding in disabled children
- Randomised comparative study of the immunogenicity of modified intradermal post-exposure rabies vaccine regimens
- The Arterial Revascularisation Trial (ART): a randomised controlled trial to compare survival following bilateral versus single internal mammary grafting in coronary revascularisation
- A cluster randomised controlled trial to assess the effectiveness of a simple marketing intervention in changing student attitudes to depression
- Scottish Unexplained Infertility Trial (SUIT): A pragmatic randomised controlled trial of clomiphene citrate versus intra-uterine insemination for the management of unexplained infertility
- The Magpie Trial: A randomised trial comparing magnesium sulphate with placebo for pre-eclampsia
- The AGIT-AD trial: Alternative treatments in the management of agitation in people with dementia
- Improving the mother-infant relationship in the context of maternal eating disorder: a randomised controlled trial
- The FITS Trial: A cluster randomised trial to test whether enhanced care reduces the need for psychotropic medication in people with severe dementia
- The IMPACT Trial: A pilot study of group cognitive behavioural therapy to prevent recurrence of late life depressive illness
- The BALANCE trial: a randomised controlled trial comparing lithium and valproate semisodium combination therapy with each individual monotherapy, as maintenance treatment for bipolar disorder
- BALANCE 2: A randomised controlled trial of treatments for recovery in bipolar depression
- The CALM-AD trial: A randomised controlled trial of a cholinesterase inhibitor in the management of agitation in dementia
- A randomised controlled trial to evaluate the feasibility and effectiveness of a nurse-led clinic compared with a medical clinic for the management of intractable functional constipation in children
- The DART-AD trial: A randomised controlled trial to compare the progression of cognitive impairment in dementia patients continuing to take or discontinued from treatment with neuroleptics (antipsychotic drugs)
- A multicentre single-blind randomised controlled trial of a mobile bearing total knee prosthesis against a fixed bearing prosthesis
- Two large simple randomised controlled trials regarding the management and complications of acute poisoning in Sri Lanka
- Treatment of relapsed childhood acute lymphoblastic leukaemia on UKALL R2 protocol: a limited centre analysis
Systematic reviews
- Systematic review of randomised controlled trials of Helicobacter pylori eradication therapies
- Systematic review of circumcision for prevention of HIV
- Systematic review: Compression stockings for preventing deep vein thrombosis in airline passengers
- Systematic review of nicotine replacement therapy
